Like Nicholai Ginovaef, Tyrell is one of the "supervisors" assigned by Umbrella to gather battle data on B.O.W. performance. According to his backstory, he originally served the French Foreign Legion, before he was apprehended by military authorities in the Netherlands for selling arms in the black market.
As Carlos, the player will encounter Tyrell in one of two different locations in Raccoon City Hospital, and his death is played out differently in each scene. If the player meets Tyrell in the basement of the hospital, he dies trying to open a safe boobytrapped with explosives. However, if the player chose to explore the second floor first, Carlos will encounter Nicholai cornering a wounded Tyrell. Tyrell blows himself up with a grenade, but Nicholai escapes by jumping through the window.
- Tyrell was thirty-two at the time of his death, according to BIOHAZARD 3 LAST ESCAPE Official Guidebook - Complete Conquest of Nemesis.
- In Nemesis, S.D. Perry's novelization of the game, Tyrell is renamed Ken Franklin and dies blowing himself up trying to kill Nicholai.